The effect of saturable binding to plasma proteins on the pharmacokinetic properties of disopyramide

Author:

Giacomini Kathleen M.,Swezey Sarah E.,Turner-Tamiyasu Kathleen,Blaschke Terrence F.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Reference23 articles.

1. A. Karim, C. Cook, R. L. Novotney, J. Zagarella, and J. Campion. Pharmacokinetics and steady-state myocardial uptake of disopyramide in the dog.Drug Metab Dispos. 6:338–345 (1978).

2. A. Karim, R. E. Ranney, and S. Kraychy. Species differences in the biotransformation of a new antiarrhythmic agent: disopyramide phosphate.J. Pharm. Sci. 61:888–893 (1972).

3. R. E. Ranney, R. R. Dean, A. Karim, and F. M. Radzialowski. Disopyramide phosphate: pharmacokinetics and pharmacologic relationships of a new antiarrhythmic agent.Arch. Int. Phamacodyn. 191:162–188 (1971).

4. A. Karim. The pharmacokinetics of Norpace.Angiology 264 (Suppl. 2, part 1): 85–98 (1975).

5. W. S. Hillis, A. Tweddel, A. R. Lorimer, and T. D. V. Lawrie. Some aspects of the clinical pharmacology of intravenous disopyramide after myocardial infarction.J. Intern. Med. Res. 4 (Suppl. 1):74–77 (1976).

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