Hemodynamic Effects of Sacubitril/Valsartan in Patients with Reduced Left Ventricular Ejection Fraction Over 24 Months: A Retrospective Study

Author:

Abumayyaleh MohammadORCID,Demmer Jonathan,Krack Carina,Pilsinger Christina,El-Battrawy Ibrahim,Behnes Michael,Aweimer Assem,Mügge Andreas,Lang Siegfried,Akin Ibrahim

Funder

Medizinische Fakultät Mannheim der Universität Heidelberg

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine,General Medicine

Reference18 articles.

1. McMurray JJ, Packer M, Desai AS, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371(11):993–1004.

2. Januzzi JL Jr, Prescott MF, Butler J, et al. Association of change in n-terminal pro-b-type natriuretic peptide following initiation of sacubitril-valsartan treatment with cardiac structure and function in patients with heart failure with reduced ejection fraction. JAMA. 2019;332:1–11.

3. Almufleh A, Marbach J, Chih S, et al. Ejection fraction improvement and reverse remodeling achieved with sacubitril/valsartan in heart failure with reduced ejection fraction patients. Am J Cardiovasc Dis. 2017;7(6):108–13.

4. Solomon SD, Claggett B, Desai AS, et al. Influence of ejection fraction on outcomes and efficacy of sacubitril/valsartan (lcz696) in heart failure with reduced ejection fraction: The prospective comparison of arni with acei to determine impact on global mortality and morbidity in heart failure (paradigm-hf) trial. Circ Heart Fail. 2016;9(3):e002744.

5. Martens P, Belien H, Dupont M, Vandervoort P, Mullens W. The reverse remodeling response to sacubitril/valsartan therapy in heart failure with reduced ejection fraction. Cardiovasc Ther. 2018;36(4):e12435.

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