Comparative Study of Alloplastic and Xenogeneic Biomaterials Used for in Dentistry-Reference-Cited by-同舟云学术

Comparative Study of Alloplastic and Xenogeneic Biomaterials Used for in Dentistry

Published:2023-05-02 Issue:2 Volume:1 Page:956-965
ISSN:2731-4812
Container-title:Biomedical Materials & Devices
language:en
Short-container-title:Biomedical Materials & Devices

Author:

Gross Jairo Marcos,Elias Carlos Nelson^ORCID,de Carvalho Jorge José,Gross Andrea,Pelegrine André Antônio,Maior Bruno Salles Sotto,de Biasi Ronaldo Sergio,da Silva Brum Igor

Abstract

AbstractBiomaterials are routinely used in dentistry for tissue engineering. The purpose of the present work is to compare the performance of a new alloplastic biomaterial (Blue-Bone®), xenogeneic biomaterial (Bio-Oss®), and a mixture of both biomaterials with 50% of autogenous bone. 32 Wistar rats underwent a surgical procedure in which a circular disc of bone was removed from the calvaria with a trephine drill 10 mm in diameter to create a critical bone defect, which was filled with the biomaterials under study. After 40 days, the animals were euthanized and the calvaria was removed for processing and analysis. Histomorphometric determination of vital mineralized tissue (VMT), no-vital mineralized tissue (NVMT), and on-mineralized tissue (NVMT) was performed. The results showed that, while cavities filled with Bio-Oss® needed to be mixed with an autogenous bone to present better performance, Blue-Bone® biomaterial does not need to be mixed with an autogenous bone to promote a more cellular and vascularized bone matrix.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s44174-023-00074-z.pdf

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