Primary urachal adenocarcinoma: a rare case report

Author:

Liu Kaihua1,Wang Hongqiang2,Yu Lei2,Wang Peitao2,Liu Zhijun3,Sun Lijiang4,Yu Hongsheng5,Li Shenqian2

Affiliation:

1. The Medical College of Qingdao University, Qingdao 266071, China

2. Department of Andrology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China

3. Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University,Qingdao 266003, China

4. Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China

5. Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China

Abstract

Abstract Primary urachal carcinoma is a very rare cancer with a poor prognosis. It generally presents as a high-grade, high-stage tumor, and in most cases the patient has developed regional or distant metastasis at the time of presentation. Here, we report a very interesting case of primary urachal adenocarcinoma with signet ring cell carcinoma in a 58-year-old male who presented with a lower abdominal mass and discomfort. In this case, urachal carcinoma was successfully treated with surgery using an extended partial bladder cystectomy approach with excision of the urachal mass and umbilicus. The patient also underwent systematic chemotherapy with 5-fluorourical and cisplatin. During the 12-month follow-up period, the patient did not experience recurrence or metastasis. Overall, we found that an organ preserving extended partial cystectomy along with chemotherapy was an optimal treatment method that helped improve the patient's quality of the life with no recurrence of cancer so far.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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5. Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation;Am J Surg Pathol,2009

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