Author:
Zhang Fuli,Wang Yadi,Xu Weidong,Jiang Huayong,Gao Junmao,Liu Qingzhi,Lu Na,Chen Diandian,Yao Bo,Hou Jun,He Heliang,Chen Jianping
Abstract
Abstract
Objective
To compute and compare the tumor control probability (TCP) of volumetric modulated arc therapy (VMAT) for breast cancer after conservative surgery based on two types of multileaf collimator (MLC) through a retrospective planning study.
Methods
For a group of 9 patients diagnosed with left breast cancer, VMAT plan based on Agility MLC and beam modulator (BM) MLC were designed. The prescription dose was 50 Gy covering at least 95% of the planning target volume, 2 Gy per fraction. TCPs were calculated according to dose-volume histogram (DVH) analysis.
Results
The TCP of the BM VMAT plan was slightly higher than that of the Agility VMAT plan (94.61% vs 94.23%) but was inferior with respect to delivery efficiency; the delivery time was reduced for Agility VMAT plan by 35% compared to BM VMAT plan.
Conclusion
For breast cancer radiation therapy after conservative surgery, BM VMAT plans provide slightly higher TCP while the delivery of Agility VMAT plans is significantly faster than the BM VMAT plans.
Publisher
Ovid Technologies (Wolters Kluwer Health)