Relacorilant, un nuovo bloccante selettivo del recettore dei glucocorticoidi
Author:
Publisher
Springer Science and Business Media LLC
Subject
Microbiology
Link
https://link.springer.com/content/pdf/10.1007/s40619-023-01361-z.pdf
Reference7 articles.
1. Brown DR, East HE, Eilerman BS et al. (2020) Clinical management of patients with Cushing syndrome treated with mifepristone: consensus recommendations. Clin Diabetes Endocrinol 6(1):18
2. Fleseriu M, Biller BM, Findling JW et al. (2012) Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing’s syndrome. J Clin Endocrinol Metab 97(6):2039–2049
3. Pivonello R, Bancos I, Feelders RA et al. (2021) Relacorilant, a selective glucocorticoid receptor modulator, induces clinical improvements in patients with Cushing syndrome: results from a prospective, open-label phase 2 study. Front Endocrinol (Lausanne) 12:662865
4. Custodio JM, Donaldson KM, Hunt HJ (2021) An in vitro and in vivo evaluation of the effect of relacorilant on the activity of cytochrome P450 drug metabolizing enzymes. J Clin Pharmacol 61(2):244–253
5. Terzolo M, Iacuaniello D, Pia A et al. (2019) SUN-463 tumor shrinkage with preoperative relacorilant therapy in two patients with Cushing disease due to pituitary macroadenomas. J Endocr Soc 3:SUN-463
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