Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Pollution,Environmental Chemistry,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11356-020-11416-5.pdf
Reference63 articles.
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2. Abdeen A, Sonoda H, El-Shawarby R, Takahashi S, Ikeda M (2014) Urinary excretion pattern of exosomal aquaporin-2 in rats that received gentamicin. Am J Physiol Ren Physiol 307:F1227–F1237. https://doi.org/10.1152/ajprenal.00140.2014
3. Afonina IS, Zhong Z, Karin M, Beyaert R (2017) Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome. Nat Immunol 18:861–869. https://doi.org/10.1038/ni.3772
4. Ali FEM, Azouz AA, Bakr AG, Abo-Youssef AM, Hemeida RAM (2018a) Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: the role of Keap-1/Nrf-2 and P(38)-MAPK/NF-κB/iNOS signaling pathway. Food Chem Toxicol 120:294–304. https://doi.org/10.1016/j.fct.2018.07.027
5. Ali FEM, Bakr AG, Abo-Youssef AM, Azouz AA, Hemeida RAM (2018b) Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis. Life Sci 207:50–60. https://doi.org/10.1016/j.lfs.2018.05.048
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