Two dechlorinated chlordecone derivatives formed by in situ chemical reduction are devoid of genotoxicity and mutagenicity and have lower proangiogenic properties compared to the parent compound

Author:

Legeay Samuel,Billat Pierre-André,Clere Nicolas,Nesslany Fabrice,Bristeau Sébastien,Faure Sébastien,Mouvet Christophe

Funder

Ministère français de l'environnement

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Pollution,Environmental Chemistry,General Medicine

Reference46 articles.

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2. Ames BN, Mccann J, Yamasaki E (1975) Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test. Mutat Res 31:347–364

3. Badach H, Nazimek T, Kaminski R, Turski W (2000) Organochlorine pesticides concentration in the drinking water from regions of extensive agriculture in Poland. Ann Agric Environ Med AAEM 7:25–28

4. Belghit H, Colas C, Bristeau S et al (2015) Liquid chromatography–high-resolution mass spectrometry for identifying aqueous chlordecone hydrate dechlorinated transformation products formed by reaction with zero-valent iron. Int J Environ Anal Chem 95:93–105. doi: 10.1080/03067319.2014.994615

5. Bjørge C, Brunborg G, Wiger R et al (1996) A comparative study of chemically induced DNA damage in isolated human and rat testicular cells. Reprod Toxicol Elmsford N 10:509–519

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