Targeting polyketide synthase gene pool within actinomycetes: new degenerate primers

Author:

Savic Miloje,Vasiljevic Branka

Publisher

Oxford University Press (OUP)

Subject

Applied Microbiology and Biotechnology,Biotechnology,Bioengineering

Reference38 articles.

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2. Aparicio JF, Fouces R, Mendes MV, Olivera N, Martin JF (2000) A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis. Chem Biol 11:895–905

3. Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thompson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CS, Kieser T, Lark L, Murphy M, Oliver K, O’Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141–147

4. Bibb MJ, Biro S, Motamedi H, Collins JF, Hutchinson CR (1989) Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of the polyketide antibiotic biosynthesis. EMBO J 8:2727–2736

5. Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, Strlm AR, Valla S, Zotchev SB (2000) Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC11455: analysis of the gene cluster and deduction of the biosynthetic pathway. Chem Biol 7:395–403

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