Stimulation of an α1-adrenergic receptor downregulates ecto-5′ nucleotidase activity on the apical membrane of RPE cells

Author:

Reigada David,Zhang Xiulan,Crespo Ana,Nguyen Johnathan,Liu Ji,Pendrak Klara,Stone Richard A.,Laties Alan M.,Mitchell Claire

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Molecular Biology

Reference39 articles.

1. Sullivan DM, Erb L, Anglade E et al. Identification and characterization of P2Y2 nucleotide receptors in human retinal pigment epithelial cells. J Neurosci Res 1997; 49(1): 43–2.

2. Peterson WM, Meggyesy C, Yu K, Miller SS. Extracellular ATP activates calcium signaling, ion, and fluid transport in retinal pigment epithelium. J Neurosci 1997; 17(7): 2324–7.

3. Maminishkis A, Jalickee S, Blaug SA et al. The P2Y(2) receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat. Investig Ophthalmol Vis Sci 2002; 43(11): 3555–6.

4. Gregory CY, Abrams TA, Hall MO. Stimulation of A2 adenosine receptors inhibits the ingestion of photoreceptor outer segments by retinal pigment epithelium. Investig Ophthalmol Vis Sci 1994; 35(3): 819–5.

5. Mitchell CH. Release of ATP by a human retinal pigment epithelial cell line: Potential for autocrine stimulation through subretinal space. J Physiol 2001; 534(1): 193–02.

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