Ketamine for Treatment of Suicidal Ideation and Reduction of Risk for Suicidal Behavior
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health
Link
http://link.springer.com/content/pdf/10.1007/s11920-016-0680-7.pdf
Reference216 articles.
1. DiazGranados N, Ibrahim L, Brutsche N, et al. Rapid resolution of suicidal ideation after a single infusion of an NMDA antagonist in patients with treatment-resistant major depressive disorder. J Clin Psychiatry. 2010;71:1605.
2. Murrough J, Soleimani L, DeWilde K, et al. Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial. Psychol Med. 2015;45:1–10. A notable study which showed that suicidal ideation was significantly reduced in patients that received ketamine versus those that were given midazolam.
3. Price RB, Mathew SJ. Does ketamine have anti-suicidal properties? Current status and future directions. CNS Drugs. 2015;29:181–8. This paper reviews the current evidence supporting rapid effects of ketamine in depression and suicide and discusses future directions for prolongation of the acute benefits of ketamine to a clinically beneficial time frame.
4. Reinstatler L, Youssef NA. Ketamine as a potential treatment for suicidal ideation: a systematic review of the literature. Drugs R D. 2015;15:37–43. Six studies and three case reports were reviewed to conclude the preliminary benefit of use of ketamine for acute treatment of depression and suicidal ideation.
5. Rajkumar R, Fam J, Yeo EY, et al. Ketamine and suicidal ideation in depression: jumping the gun? Pharmacol Res. 2015;99:23–35. This review paper looks at the molecular mechanism of ketamine on the brain, evaluates several rodent and human studies and concludes the limitation of ketamine and the need for studies for further evaluation of long term benefits of ketamine.
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