The impact of residual symptoms on outcome of major depression
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health
Link
http://link.springer.com/content/pdf/10.1007/s11920-005-0065-9.pdf
Reference49 articles.
1. Lee AS, Murray RM: The long-term outcome of Maudsley depressives. Br J Psychiatry 1988, 153:741–751. In this seminal long-term study of outcomes of depression using actuarial methods, 89 consecutive admissions with depression in a tertiary referral center were followed up after 18 years. Less than 20% had remained well, one third had suffered an unnatural death or severe chronic disability and a high proportion suffered an unnatural death.
2. Keller MB, Lavori PW, Mueller TI, et al.: Time to recovery, chronicity, and levels of psychopathology in major depression. A 5-year prospective follow-up of 431 subjects. Arch Gen Psychiatry 1992, 49:809–816.
3. Kiloh LG, Andrews G, Neilson M: The long-term outcome of depressive illness. Br J Psychiatry 1988, 153:752–757.
4. Lee AS: Better outcomes for depressive disorders? Psychol Med 2003, 33:769–774.
5. Judd LL, Akiskal HS, Maser JD, et al.: A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders. Arch Gen Psychiatry 1998, 55:694–700. The weekly symptom level of 431 patients with major depression at five centers was rated prospectively over a period of 12 years. The amount of time spent at each level was rated. Patients spent 43% of time at combined minor depressive or subsyndromal symptom level, three times more than at a major depression level. Symptom levels changed on average twice per year.
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