Bioavailability and Pharmacokinetic Parameters of a Formulation Containing Secoisolariciresinol Diglucoside–Rich Extract

Author:

Gadgoli ChhayaORCID,Bhandekar SiddhiORCID,Bhere HarshalaORCID,Naik ArchanaORCID

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference23 articles.

1. Carreau C, Flouriot G, Bennetau-Pelissero C, Potier M (2008) Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERα transcriptional activation in human breast cancer cells. J Steroid Biochem Mol Biol 110:176–185. https://doi.org/10.1016/j.jsbmb.2008.03.032

2. De Silva SF, Alcorn J (2019) Flaxseed lignans as important dietary polyphenols for cancer prevention and treatment: chemistry, pharmacokinetics, and molecular targets. Pharmaceuticals 12:68. https://doi.org/10.3390/ph12020068

3. Demark-Wahnefried W, Polascik TJ, George SL, Switzer BR, Madden JF, Ruffin MT IV, Snyder DC, Owzar K, Hars V, Albala DM, Walther PJ, Robertson CN, Moul JW, Dunn BK, Brenner D, Minasian L, Stella P, Vollmer RT (2008) Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. Cancer Epidemiol Biomarkers Prev 17:3577–3587. https://doi.org/10.1158/1055-9965.EPI-08-0008

4. Gang SH, Cheng L, Li-Qiang WA, Zhang LH, Bao-De SH, Wei-Bo LI, Juan-Juan LI, Zheng J, Rong XU, Hai-Long YU (2016) Formulation of dried lignans nanosuspension with high redispersibility to enhance stability, dissolution, and oral bioavailability. Chin J Nat Med 14:757–768. https://doi.org/10.1016/S1875-5364(16)30090-5

5. Hu C, Yuan YV, Kitts DD (2007) Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro. Food Chem Toxicol 45:2219–2227. https://doi.org/10.1016/j.fct.2007.05.017

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