Protective Effect of Schisandra chinensis Extract Against Ethanol-Induced Gastric Ulcers in Mice by Promoting Anti-inflammatory and Mucosal Defense Mechanisms

Author:

Si Wen-zhangORCID,Hu Xin-xinORCID,Shen ChenORCID,Luo Ming-xiaoORCID,Xuan Yan-hanORCID,Fu Hai-jingORCID,Xing GuiyingORCID,Zhang Hua-fangORCID,Zhang JianORCID,Liu ZhengORCID

Publisher

Springer Science and Business Media LLC

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference22 articles.

1. Alzokaky AA, Abdelkader EM, El-Dessouki AM, Khaleel SA, Raslan NA (2020) C-phycocyanin protects against ethanol-induced gastric ulcers in rats: role of HMGB1/NLRP3/NF-kappaB pathway. Basic Clin Pharmacol Toxicol. https://doi.org/10.1111/bcpt.13415

2. Arab HH, Salama SA, Omar HA, El-Shaimaa AA, Maghrabi IA (2015) Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions. PLoS One 10:e0122417. https://doi.org/10.1371/journal.pone.0122417

3. Chen P, Shen Y, Shi H, Ma X, Lin B, Xiao T, Wu F, Zhu J, Li Z, Xiao J, Li X, Zhang H, Geng F (2016) Gastroprotective effects of Kangfuxin-against ethanol-induced gastric ulcer via attenuating oxidative stress and ER stress in mice. Chem Biol Interact 260:75–83. https://doi.org/10.1016/j.cbi.2016.10.021

4. de Araujo ERD, Guerra DCB, Araujo DFS, Araujo AA, Fernandes JM, Araujo Junior RF, Silva VC, Carvalho TG, Ferreira LS, Zucolotto SM (2018) Gastroprotective and antioxidant activity of Kalanchoe brasiliensis and Kalanchoe pinnata leaf juices against indomethacin and ethanol-induced gastric lesions in rats. Int J Mol Sci 19:1265. https://doi.org/10.3390/ijms19051265

5. Dilshara MG, Jayasooriya RGPT, Kang C-H, Lee S, Park SP, Jeong J-W, Choi YH, Seo YT, Jang YP, Kim G-Y (2013) Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. Environ Toxicol Pharmacol 36:256–264. https://doi.org/10.1016/j.etap.2013.04.005

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