Quercetin Simultaneously Inhibited Cytochrome P450 and P-Glycoprotein to Improve the Pharmacokinetics of Osthole in Rat Plasma
Author:
Funder
National Natural Science Foundation of China
Guangzhou Municipal Science and Technology Project
Publisher
Springer Science and Business Media LLC
Subject
General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s43450-023-00487-3.pdf
Reference30 articles.
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3. Borska S, Sopel M, Chmielewska M, Zabel M, Dziegiel P (2010) Quercetin as a potential modulator of P-glycoprotein expression and function in cells of human pancreatic carcinoma line resistant to daunorubicin. Molecules 15:857–870. https://doi.org/10.3390/molecules15020857
4. Cai H, Luo Y, Yan X, Ding P, Huang Y, Fang S, Zhang R, Chen Y, Guo Z, Fang J, Wang Q, Xu J (2018) The mechanisms of Bushen-Yizhi formula as a therapeutic agent against Alzheimer’s disease. Sci Rep 8:3104. https://doi.org/10.1038/s41598-018-21468-w
5. Chen J, Liu J, Huang Y, Li R, Ma C, Zhang B, Wu F, Yu W, Zuo X, Liang Y, Wang Q (2021) Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibition. Drug Metab Rev 53:491–507. https://doi.org/10.1080/03602532.2021.1917598
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