Pinosylvin Inhibits Esophageal Squamous Cell Carcinoma Migration and Invasion by Regulating STX6/ITGA3/VASP Pathway
Author:
Funder
Natural Science Foundation of Jiangsu Province
Publisher
Springer Science and Business Media LLC
Subject
General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s43450-022-00354-7.pdf
Reference22 articles.
1. Chen MK, Liu YT, Lin JT, Lin CC, Chuang YC, Lo YS, Hsi YT, Hsieh MJ (2019) Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway. Biomed Pharmacother 117:109160. https://doi.org/10.1016/j.biopha.2019.109160
2. Chuang YC, Hsieh MC, Lin CC, Lo YS, Ho HY, Hsieh MJ, Lin JT (2021) Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelialmesenchymal transition and inhibition of MMP2. Oncol Rep 46:143. https://doi.org/10.3892/or.2021.8094
3. Desgrosellier JS, Cheresh DA (2010) Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 10:9–22. https://doi.org/10.1038/nrc2748
4. Du J, Liu X, Wu Y, Zhu J, Tang Y (2016) Essential role of STX6 in esophageal squamous cell carcinoma growth and migration. Biochem Biophys Res Commun 472:60–67. https://doi.org/10.1016/j.bbrc.2016.02.061
5. Huang F, Ma G, Zhou X, Zhu X, Yu X, Ding F, Cao X, Liu Z (2020) Depletion of LAMP3 enhances PKA-mediated VASP phosphorylation to suppress invasion and metastasis in esophageal squamous cell carcinoma. Cancer Lett 479:100–111. https://doi.org/10.1016/j.canlet.2020.03.014
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