Organ Fabrication: Progress and Hurdles to Overcome
Author:
Funder
Sumitomo Pharma Co., Ltd
SCREEN Holdings Co., Ltd
Publisher
Springer Science and Business Media LLC
Subject
Transplantation,Nephrology,Hepatology,Immunology,Surgery
Link
https://link.springer.com/content/pdf/10.1007/s40472-022-00372-3.pdf
Reference20 articles.
1. Porrett PM, Orandi BJ, Kumar V, Houp J, Anderson D, Cozette Killian A, et al. First clinical-grade porcine kidney xenotransplant using a human decedent model. Am J Transplant. 2022;22:1037–53. https://doi.org/10.1111/ajt.16930.
2. Montgomery RA, Stern JM, Lonze BE, Tatapudi VS, Mangiola M, Wu M, et al. Results of two cases of pig-to-human kidney xenotransplantation. N Engl J Med. 2022;386:1889–98. https://doi.org/10.1056/NEJMoa2120238.
3. • Reardon S. First pig-to-human heart transplant: what can scientists learn? Nature. 2022;601:305–6. https://doi.org/10.1038/d41586-022-00111-9*(Article that describes the current barriers to xenotransplantation).
4. •• Kobayashi E, Tohyama S, Fukuda K. Organ fabrication using pigs as an in vivo bioreactor. Keio J Med. 2020;69:30–6. https://doi.org/10.2302/kjm.2019-0006-OA. **(Article by Eiji Kobayashi, the author of this paper, which summarizes the concept of creating human organs in the bodies of living animals).
5. Yamaguchi T, Sato H, Kato-Itoh M, Goto T, Hara H, Sanbo M, et al. Interspecies organogenesis generates autologous functional islets. Nature. 2017;542:191–6. https://doi.org/10.1038/nature21070.
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