Evasion of Pre-Existing Immunity to Cas9: a Prerequisite for Successful Genome Editing In Vivo?
Author:
Funder
University of Oxford
Publisher
Springer Science and Business Media LLC
Subject
Transplantation,Nephrology,Hepatology,Immunology,Surgery
Link
http://link.springer.com/content/pdf/10.1007/s40472-019-00237-2.pdf
Reference60 articles.
1. Travis J. Making the cut: CRISPR-genome editing technology shows its power. Science. 2015;350:1456–7.
2. Wang D, Mou H, Li S, Li Y, Hough S, Tran K, et al. Adenovirus-mediated somatic genome editing of Pten by CRISPR/Cas9 in mouse liver in spite of Cas9 specific immune responses. Hum Gene Ther. 2015;26:432–42.
3. Wang F, Qi LS. Applications of CRISPR genome engineering in cell biology. Trends Cell Biol. 2016;26:875–88.
4. Yin H, Wen X, Chen S, Bogorad RL, Benedetti E, Grompe M, et al. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nat Biotechnol. 2014;32:551–3.
5. • Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. 2017;550:67–73. A groundbreaking study which constitutes the first application of genome editing to human embryos, revealing an important role for the pluripotency gene OCT4 in embryogenesis.
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