CAR-Tregs as a Strategy for Inducing Graft Tolerance
Author:
Publisher
Springer Science and Business Media LLC
Subject
Transplantation,Nephrology,Hepatology,Immunology,Surgery
Link
https://link.springer.com/content/pdf/10.1007/s40472-020-00285-z.pdf
Reference66 articles.
1. •• Tang Q, Bluestone JA. Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harb Perspect Med. 2013. https://doi.org/10.1101/cshperspect.a015552Comprehensive review about Treg therapy, the transfer into the clinic and the application in transplantation.
2. Brennan TV, Tang Q, Liu F-C, Hoang V, Bi M, Bluestone JA, et al. Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts. J Surg Res. 2011;169:e69–75. https://doi.org/10.1016/j.jss.2011.03.021.
3. Sagoo P, Ali N, Garg G, Nestle FO, Lechler RI, Lombardi G. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci Transl Med. 2011;3:83ra42. https://doi.org/10.1126/scitranslmed.3002076.
4. • Tsang JY-S, Tanriver Y, Jiang S, Xue S-A, Ratnasothy K, Chen D, et al. Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice. J Clin Invest. 2008;118:3619–28. https://doi.org/10.1172/JCI33185First report of engineered Tregs using TCR for conferring indirect allo-reactivity in a mouse model of transplantation.
5. Joffre O, Santolaria T, Calise D, Al Saati T, Hudrisier D, Romagnoli P, et al. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat Med. 2008;14:88–92. https://doi.org/10.1038/nm1688.
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