Approaches to Mitigate Longer Cold Ischemic Times and Increased Rates of Delayed Graft Function Associated With the Revised Kidney Allocation System

Author:

York Tyler,Eletta Olanrewaju,Kurian Joshua,Shah Mital,Puri Sonika,Bongu Advaith

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Nephrology,Hepatology,Immunology,Surgery

Reference64 articles.

1. Wang JH, Skeans MA, Israni AK. Current status of kidney transplant outcomes: dying to survive. Adv Chronic Kidney Dis. 2016;23(5):281–6.

2. Gibbons A, et al. Changes in quality of life (QoL) and other patient-reported outcome measures (PROMs) in living-donor and deceased-donor kidney transplant recipients and those awaiting transplantation in the UK ATTOM programme: a longitudinal cohort questionnaire survey with additional qualitative interviews. BMJ Open. 2021;11(4):e047263.

3. Rhoades T. Eliminate the use of DSA and Region in kidney allocation policy. Kidney Transplantation Committee. Organ Procurement and Transplantation Network. 2019. https://optn.transplant.hrsa.gov/policies-bylaws/public-comment/eliminate-the-use-of-dsa-and-region-in-kidney-allocation-policy/

4. Bradbrook KD, Booker S, Dolan T, Gauntt K. UNOS Research Department. Eliminate use of DSA and region from kidney allocation. Two year post-implementation monitoring report. Kidney Transplantation Committee Meeting, Organ Procurement and Transplantation Network. 2023. https://optn.transplant.hrsa.gov/media/4mhfm3oq/eliminate_use_of_dsa_and_region_from_kidney_allocation_two_year_post_implementation_monitoring_report_2yr.pdf. This is a committee meeting data report that serves as the foundational basis of the paper. This committee meeting data report demonstrated the increased access to kidney transplants after the new allocation system was implemented, but also demonstrated the shortcomings associated such as longer CIT and higher DGF.

5. Debout A, et al. Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation. Kidney Int. 2015;87(2):343–9.

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