High-glucose-induced apoptosis, ROS production and pro-inflammatory response in cardiomyocytes is attenuated by metformin treatment via PP2A activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12038-020-00096-5.pdf
Reference29 articles.
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3. Da Silva D, Ausina P, Alencar EM, Coelho WS, Zancan P and Sola-Penna M 2012 Metformin reverses hexokinase and phosphofructokinase downregulation and intracellular distribution in the heart of diabetic mice. IUBMB Life 64 766–774
4. Demir U, Koehler A, Schneider R, Schweiger S and Klocker H 2014 Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells. BMC Cancer 14 52
5. Du H, Huang Y, Zaghlula M, Walters E, Cox TC and Massiah MA 2013 The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A. J. Biol. Chem. 288 21341–21350
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