Hypoxia stimulates invasion and migration of human cervical cancer cell lines HeLa/SiHa through the Rab11 trafficking of integrin αvβ3/FAK/PI3K pathway-mediated Rac1 activation

Author:

Xu Hao,Yuan Yuan,Wu Wenqian,Zhou Min,Jiang Qian,Niu Linjun,Ji Jiayin,Liu Nianli,Zhang Longzhen,Wang Xia

Publisher

Springer Science and Business Media LLC

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference29 articles.

1. Avraham H, Park SY, Schinkmann K and Avraham S 2000 RAFTK/Pyk2-mediated cellular signalling. Cell. Signal. 12 123–133

2. Bae KM, Dai Y, Vieweg J and Siemann DW 2015 Hypoxia regulates SOX2 expression to promote prostate cancer cell invasion and sphere formation. Am. J. Cancer Res. 6 1078–1088

3. Bhuin T and Roy JK 2015 Rab11 in disease progression. Int. J. Mol. Cell. Med. 4 1–8

4. Binker MG, Gaisano HY, Cosen RHD and Binker LIC 2010 Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2. Biochem. Biophys. Res. Commun. 393 371–376

5. Brown JM 1999 The hypoxic cell: a target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res. 59 5863–5870

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