MALT Lymphoma in Children: Case Report and Review of the Literature

Author:

Mo Jun Q.1,Dimashkieh Haytham2,Mallery Susan R.3,Swerdlow Steven H.4,Bove Kevin E.1

Affiliation:

1. Division of Pathology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA

2. Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, P.O. Box 670529 Cincinnati, OH 45267-0529, USA

3. Department of Oral Surgery and Pathology, Ohio State University College of Dentistry, P.O. Box 638, Columbus, OH 43272-8721, USA

4. Division of Hematopathology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma predominantly occurs in adults, and is rare in children. We report a case of MALT lymphoma involving minor salivary gland of the lip in an otherwise healthy 12-year-old boy. This is the second case report of MALT lymphoma of minor salivary gland in an immunocompetent child. Of 24 cases of MALT lymphomas in children reported in the English literature, parotid MALT lymphomas in human immunodeficiency virus (HIV) patients and H. pylori infection-associated gastric MALT lymphomas are the most common. As in adult cases, most MALT lymphomas in the pediatric age group are localized and follow an indolent clinical course, respond well to therapy, and have an excellent outcome.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology, and Child Health

Reference33 articles.

1. HarrisNL, JaffeES, SteinH, VardimanJW. Pathology and Genetics of Tumours of the Haemopoeitic and Lymphoid Tissues, WHO Classification of Tumors. Lyon: International Agency for Research on Cancer Press, 2001.

2. Parotid MALT lymphoma in HIV infected children.

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