Endodermal Sinus Tumor of the Parotid Gland in a Child

Author:

Sredni Simone Treiger12,da Cunha Isabela Werneck1,de Carvalho Filho Nevigolino Pereira3,Magrin José4,Pinto Clovis Antonio Lopes1,Lopes Luis Fernando23

Affiliation:

1. Department of Pathology, Hospital do Cäncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

2. Laboratory of Cancer Genetics, Ludwig Institute for Cancer Research, Rua Professor Antonio Prudente 109, 4th Floor, São Paulo 01509-010, Brazil

3. Department of Pediatrics, Hospital do Cãncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

4. Department of Head and Neck Surgery, Hospital do Câncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

Abstract

We report a case of a 16-month-old girl with a primary endodermal sinus tumor (EST) of the parotid gland. The girl was admitted to the hospital with a left side cervical tumor with a quick growth (within 3 wk). The tumor was surgically resected. The gross examination showed a 7.0-cm hemorrhagic and fragmentized mass. Diagnosis of an EST was established on the hematoxylin and eosinstained slides from the resected material. Elevated serum alpha-fetoprotein (AFP) levels were detected and follow-up examinations of the patient did not show ESTs in other locations or other manifestations due to the tumor. The patient received chemotherapy after the surgery and remained alive without evidence of disease at the time of this writing (2 years after the diagnosis). As far as we know, this is the second report in the literature of a parotid gland's EST.

Publisher

SAGE Publications

Subject

General Medicine,Pathology and Forensic Medicine,Pediatrics, Perinatology and Child Health

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1. Yolk sac tumor of the parotid gland in a child and its differentials;Journal of Indian Association of Pediatric Surgeons;2022-09

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3. Germ Cell Tumors of Miscellaneous Extragonadal Sites;Pathology and Biology of Human Germ Cell Tumors;2017

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