Methods for Measuring Risk for Type 2 Diabetes in Youth: the Oral Glucose Tolerance Test (OGTT)-Reference-Cited by-同舟云学术

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Methods for Measuring Risk for Type 2 Diabetes in Youth: the Oral Glucose Tolerance Test (OGTT)

Published:2018-06-16 Issue:8 Volume:18 Page:
ISSN:1534-4827
Container-title:Current Diabetes Reports
language:en
Short-container-title:Curr Diab Rep

Author:

Chen Melinda E.,Aguirre Rebecca S.,Hannon Tamara S.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/article/10.1007/s11892-018-1023-3/fulltext.html

Reference74 articles.

1. D'Adamo E, Caprio S. Type 2 diabetes in youth: epidemiology and pathophysiology. Diabetes Care. 2011;34(Suppl 2):S161–5.

2. Hannon TS, Arslanian SA. The changing face of diabetes in youth: lessons learned from studies of type 2 diabetes. Ann N Y Acad Sci. 2015;1353:113–37.

3. Bacha F, Lee S, Gungor N, Arslanian SA. From pre-diabetes to type 2 diabetes in obese youth: pathophysiological characteristics along the spectrum of glucose dysregulation. Diabetes Care. 2010;33(10):2225–31.

4. •• Chen ME, Chandramouli AG, Considine RV, Hannon TS, Mather KJ. Comparison of beta-cell function between overweight/obese adults and adolescents across the spectrum of glycemia. Diabetes Care. 2018;41(2):318–25. This manuscript describes the comparison of adult and adolescent OGTT test results with model-derived and direct measures of insulin secretion and insulin sensitivity across a spectrum of glucose tolerance levels. Adolescents have much lower insulin sensitivity as compared with adults, whereas, adults have poorer beta-cell responses to glucose at earlier stages of glucose intolerance. These results may suggest different approaches to diabetes prevention in youths versus adults.

5. • Hannon TS, Kahn SE, Utzschneider KM, Buchanan TA, Nadeau KJ, Zeitler PS, et al. Review of methods for measuring beta-cell function: design considerations from the Restoring Insulin Secretion (RISE) Consortium. Diabetes Obes Metab. 2018;20(1):14–24. A current review of intravenous and oral techniques for measuring beta-cell function.

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