Pancreatic islet xenotransplantation: Barriers and prospects
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11892-003-0027-8.pdf
Reference50 articles.
1. Bennet W, Sundberg B, Groth CG, et al.: Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? Diabetes 1999, 48:1907–1914.
2. Ozmen L, Ekdahl KN, Elgue G, et al.: Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 2002, 51:1779–1784.
3. Badet L, Titus T, Metzen E, et al.: The interaction between primate blood and mouse islets induces accelerated clotting with islet destruction. Xenotransplantation 2002, 9:91–96.
4. Bennet W, Sundberg B, Lundgren T, et al.: Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. Transplantation 2000, 69:711–719. Indicates that a rapid coagulation cascade found to occur in response to allogeneic islets can also impact islet xenografts.
5. Inverardi L, Clissi B, Stolzer AL, et al.: Human natural killer lymphocytes directly recognize evolutionarily conserved oligosaccharide ligands expressed by xenogeneic tissues. Transplantation 1997, 63:1318–1330.
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