The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells-Reference-Cited by-同舟云学术

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The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells

Published:2017-07-14 Issue:5 Volume:12 Page:677-687
ISSN:1776-2596
Container-title:Targeted Oncology
language:en
Short-container-title:Targ Oncol

Author:

Zhang Leisi,Zhou Yong,Chen Kai,Shi Pengcheng,Li Yin,Deng Manman,Jiang Zhiwu,Wang Xiangmeng,Li Peng,Xu Bing^ORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

The Guangdong Provincial Basic Research Program

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Oncology

Link

http://link.springer.com/article/10.1007/s11523-017-0509-2/fulltext.html

Reference40 articles.

1. Klco JM, Miller CA, Griffith M, et al. Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia. JAMA. 2015;314:811–22.

2. Walter RB, Kantarjian HM, Huang X, et al. Effect of complete remission and responses less than complete remission on survival in acute myeloid leukemia: a combined eastern cooperative oncology group, southwest oncology group, and M. D. Anderson cancer center study. J. Clin Oncol. 2010;28:1766–71.

3. Hu Y, Li S. Survival regulation of leukemia stem cells. Cell Mol Life Sci. 2016;5:1039–50.

4. Vo T, Ryan J, Carrasco R, et al. Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML. Cell. 2012;151:344–55.

5. Guzman ML, Allan JN. Concise review: leukemia stem cells in personalized medicine. Stem Cells. 2014;32:844–51.

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