The mTOR pathway inhibitor RAD001 (everolimus) is highly efficacious in tamoxifen-sensitive and -resistant breast cancer xenografts
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s11523-007-0054-5.pdf
Reference44 articles.
1. Vignot S, Faivre S, Aguirre D, Raymond E (2005) mTOR-targeted therapy of cancer with rapamycin derivatives. Ann Oncol 16:525–537
2. Dancey JE (2005) Inhibitors of the mammalian target of rapamycin. Expert Opin Investig Drugs 14:313–328
3. Chan S (2004) Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. Br J Cancer 91:1420–1424
4. Hay N (2005) The Akt-mTOR tango and its relevance to cancer. Cancer Cell 8:179–183
5. Sarbassov dos D, Ali SM, Sabatini DM (2005) Growing roles for the mTOR pathway. Curr Opin Cell Biol 17:596–603
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2. The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8;Acta Pharmacologica Sinica;2018-01-18
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