Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies-Reference-Cited by-同舟云学术

Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies

Published:2019-02 Issue:1 Volume:14 Page:43-55
ISSN:1776-2596
Container-title:Targeted Oncology
language:en
Short-container-title:Targ Oncol

Author:

de Jonge Maja J. A.,Steeghs Neeltje,Lolkema Martijn P.,Hotte Sebastien J.,Hirte Hal W.,van der Biessen Diane A. J.,Abdul Razak Albiruni R.,De Vos Filip Y. F. L.,Verheijen Remy B.,Schnell David,Pronk Linda C.,Jansen Monique,Siu Lillian L.

Funder

Boehringer Ingelheim

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Oncology

Link

http://link.springer.com/article/10.1007/s11523-018-00617-1/fulltext.html

Reference40 articles.

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2. Sulzmaier FJ, Jean C, Schlaepfer DD. FAK in cancer: mechanistic findings and clinical applications. Nat Rev Cancer. 2014;14(9):598–610.

3. Tai YL, Chen LC, Shen TL. Emerging roles of focal adhesion kinase in cancer. Biomed Res Int. 2015;2015:690690.

4. Lee BY, Timpson P, Horvath LG, Daly RJ. FAK signaling in human cancer as a target for therapeutics. Pharmacol Ther. 2015;146:132–49.

5. Kornberg LJ. Focal adhesion kinase and its potential involvement in tumor invasion and metastasis. Head Neck. 1998;20(8):745–52.

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