Pharmacokinetic/pharmacodynamic interactions of intensive cyclophosphamide, cisplatin, and BCNU in patients with breast cancer

Author:

Jones Roy B.,Matthes Steven,Dufton Christopher,Bearman Scott I.,Stemmer Salomon M.,Meyers Susan,Shpall Elizabeth J.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference9 articles.

1. Peters WP, Eder JP, Henner WD, Bast RC Jr, Schnipper L, Frei E III: Novel toxicities associated with high-dose combination alkylating agents and autologous bone marrow support.In: Dicke C, Spitzer G, Zander A (eds) Autologous Bone Marrow Transplantation: Proceedings of the First International Symposium. Houston, University of Texas MD Anderson Hospital and Tumor Institute, 1985, pp 231-236

2. Jones RB, Matthes S: Pharmacokinetics.In: Armitage JO, Antman KH (eds) High-Dose Cancer Therapy: Pharmacology, Hematopoietins, and Stem Cells. Williams and Wilkins, Baltimore, 1992, pp 43?60

3. Jones RB, Shpall EJ, Ross M, Coniglio D, Affronti ML, Peters WP: High-dose carboplatin, cyclophosphamide, and BCNU with autologous bone marrow support: excessive hepatic toxicity. Cancer Chemother Pharmacol 26:155?156, 1990

4. Ayash LS, Wright JE, Tretyakov O, Gonin R, Elisa A, Wheeler C, Eder JP, Rowosky A, Antman K, Frei E: Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and antitumor response. J Clin Oncol 10:995?1000, 1992

5. Jones RB, Matthes SM, Shpall EJ, Stemmer S, Bearman SI: Acute lung injury following high-dose cyclophosphamide, cisplatin, and BCNU: pharmacodynamic evaluation of BCNU. J Natl Cancer Inst (in press)

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