Blockade of PD-1 and TIM-3 immune checkpoints fails to restore the function of exhausted CD8+ T cells in early clinical stages of chronic lymphocytic leukemia-Reference-Cited by-同舟云学术

Blockade of PD-1 and TIM-3 immune checkpoints fails to restore the function of exhausted CD8+ T cells in early clinical stages of chronic lymphocytic leukemia

Published:2020-07-24 Issue:5 Volume:68 Page:269-279
ISSN:0257-277X
Container-title:Immunologic Research
language:en
Short-container-title:Immunol Res

Author:

Rezazadeh Hadiseh,Astaneh Mojgan,Tehrani Mohsen,Hossein-Nataj Hadi,Zaboli Ehsan,Shekarriz Ramin,Asgarian-Omran Hossein^ORCID

Funder

National Institute for Medical Research Development

Mazandaran University of Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Immunology

Link

https://link.springer.com/content/pdf/10.1007/s12026-020-09146-4.pdf

Reference42 articles.

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3. Eichhorst B, Robak T, Montserrat E, Ghia P, Hillmen P, Hallek M, et al. Chronic lymphocytic leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2015;26(suppl_5):v78–84.

4. Sun C, Dotti G, Savoldo B. Utilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies. Blood. 2016;127(26):3350–9.

5. Alsaab HO, Sau S, Alzhrani R, Tatiparti K, Bhise K, Kashaw SK, et al. PD-1 and PD-L1 checkpoint signaling inhibition for cancer immunotherapy: mechanism, combinations, and clinical outcome. Front Pharmacol. 2017;8:561.

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