Stereoselective HPLC assay of TJ0711 enantiomers by precolumn derivatization with GITC using UV detection and its application in pharmacokinetics in rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Biomedical Engineering,Biomaterials,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s11596-009-0407-7.pdf
Reference20 articles.
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3. Eichelbaum M. Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man. Biochem Pharmacol, 1998,37(1):93–96
4. Jamali F, Mehvar R, Pasutto FM. Enantioselective aspects of drug action and disposition:therapeutic pitfalls. J Pharm Sci, 1989,78(9):695–715
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2. Accurate determination of a novel vasodilatory β -blocker TJ0711 using LC-MS/MS: Resolution of an isobaric metabolite interference in dog plasma;Biomedical Chromatography;2018-02-12
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4. Influence of Dose and Route of Administration on the Enantioselective Pharmacokinetics of TJ0711 Hydrochloride in Rats;Chirality;2014-10-15
5. In vitro enantioselective metabolism of TJ0711 hydrochloride by human liver microsomes using a novel chiral liquid chromatography–tandem mass spectrometry method;Journal of Chromatography B;2012-04
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