Single dose and multiple dose pharmacokinetics of 2′-fluoro-2′,3′-dideoxyadenosine and 2′-fluoro-2′,3′-dideoxyinosine, anti-HIV agents, in rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/BF03190041.pdf
Reference11 articles.
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2. Pauwels R., Baba M., Herdewijn P. et al. (1988): Investigations on the anti-HIV activity of 2′,3′-dideoxyanalogues with modifications in either the pentose or purine moiety. Biochem. Pharmacol., 37, 1317–1325.
3. Mitsuya H., Broder S. (1986): Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy associated virus (HTLV-III/LAV) by 2′,3′-nucleosides. Proc. Natl. Acad. Sci. USA, 83, 1911–1915.
4. Marquez V.E., Tseng C.K-H., Kelley J.A. et al. (1987): 2′,3′-Dideoxy-2′-fluoro-ARA-A. An acid stable purine nucleoside active against human immunodeficiency virus (HIV). Biochem. Pharmacol., 36, 2719–2722.
5. Chen M.S., Oshana S.C. (1987): Inhibition of HIV reverse transcriptase by 2′,3′-dideoxynucleoside triphosphates. Biochem. Pharmacol., 36, 4361–4362.
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1. Nucleoside Reverse Transcriptase Inhibitors, Mitochondrial Dna and Aids Therapy;Antiviral Therapy;2005-02
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