First pass hydroxylation of nortriptyline: Concentrations of parent drug and major metabolites in plasma

Author:

Alv�n G.,Borg� O.,Lind M.,Palm�r L.,Siwers B.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference18 articles.

1. Alexanderson, B.: Pharmacokinetics of nortriptyline in man after single and multiple oral doses: The predictability of steady-state plasma concentrations from single dose plasma level data. Europ. J. clin. Pharmacol.5, 44?54 (1972)

2. Alexanderson, B., Borgå, O., Alván, G.: The availability of orally administered nortriptyline. Europ. J. clin. Pharmacol.5, 181?185 (1973)

3. Alván, G., Lind, M., Mellström, B., von Bahr, C.: Importance of ?first pass elimination? for interindividual differences in equilibrium concentrations of the adrenergic beta-receptor antagonist alprenolol. J. Pharmacokin. Biopharm. Submitted

4. Alván, G., Sjöqvist, F.: Behandling av akuta intoxikationer ? farmakokinetiska behandlingsprinciper. Läkartidningen68, (suppl I) 65?78 (1971)

5. Borgå, O., Palmér, L., Linnarsson, A., Holmstedt, B.: Quantitative determination of nortriptyline and desmethylnortriptyline in human plasma by combined gas chromatography ? mass spectrometry. Anal. Letters4, 837?849 (1971)

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