Stopped-Flow Studies of Human Aldose Reductase Reveal which Enzyme form Predominates During Steady-State Turnover in Either Reaction Direction

Author:

Grimshaw Charles E.,Lai Chung-Jeng

Publisher

Springer US

Reference30 articles.

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2. Barshop, B.A., Wrenn, R.F., & Frieden, C. (1983) Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM — A flexible, portable system. Anal. Biochem. 130:134–145.

3. Bhatnagar, A., Das, B., Gavva, S.R., Cook, P.F., and Srivastava, S.K. (1988) The kinetic mechanism of human placental aldose reductase and aldehyde reductase II. Arch. Biochem. Biophys. 261:264–274.

4. Bhatnagar, A., Liu, S.-Q., Ueno, N., Chakrabarti, B., and Srivastava, S.K. (1994) Human placental aldose reductase: Role of Cys-298 in substrate and inhibitor binding. Biochim. Biophys. Acta 1205:207–214.

5. Bohren, K.M., Page, J.L., Shankar, R., Henry, S.P., and Gabbay, K.H. (1991) Expression of human aldose and aldehyde reductase. Site-directed mutagenesis of a critical lysine 262. J. Biol. Chem. 266:24031–24037.

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