Combination Therapy with the Antiandrogen Flutamide and the LHRH Agonist [D-Trp6, des-Gly-NH2 10]LHRH Ethylamide in Prostate Cancer: Rationale and 5-Year Clinical Experience

Author:

Labrie Fernand,Dupont André,Bélanger Alain,Simard Jacques,Labrie Claude,Poulin Richard,Luthy Isabel,Veilleux Raymonde,Lacoste Daniel,Marchetti Bianca,Cusan Lionel,Manhès Gilles,Monfette Gérard,Emond Jean

Publisher

Springer US

Reference51 articles.

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2. Bartsch, W., Knabbe, M., and Voigt, K.D., 1983, Regulation and compart-mentalization of androgens in rat prostate and muscle. J. Steroid Biochem., 19:929.

3. Baulieu, E.E., 1963, Studies on the secretion and interconversion of the androgens. Rec. Progr. Horm. Res., 19:306.

4. Bélanger, A., Dupont, A., and Labrie, F. 1984, Inhibition of basal and adrenocorticotropin-stimulated plasma levels of adrenal androgens after treatment with an antiandrogen in castrated patients with prostatic cancer. J. Clin. Endocrinol. Metab., 59: 422.

5. Brendler, H., 1959, Current Cancer Concepts: therapy with orchiectomy or estrogens or both. JAMA, 210:1074.

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