Humanization of an Anti-Mucin Antibody for Breast and Ovarian Cancer Therapy

Author:

Baker T. S.,Caskey-Finney H. M.,King D. J.,Lawson A. D. G.,Lyons A.,Mountain A.,Rolfe M. R.,Sehdev M.,Yarranton G. T.,Adair J. R.,Bose C. C.,Owens R. J.

Publisher

Springer US

Reference70 articles.

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2. Adair, J.R., 1992, Engineering antibodies for therapy, Immunological Reviews, 130: 1.

3. Adair, J.R., Athwal, D.S., and Emtage, J.S., 1991, Humanised antibodies, WO91/09967.

4. Angal, S., King, D.J., Bodmer, M.W., Turner, A., Lawson, A.D.G., Pedley, B., Roberts, G., and Adair, J.R., 1992, A single amino acid substitution abolishes the heterogeneity of a chimeric mouse/human (IgG4) antibody, Mol. Immunol, in press.

5. Atherton, E., and Sheppard, R.C., 1989, RSolid Phase Synthesis: A practical ApproachS, IRL Press, Oxford.

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