Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis

Author:

Lutz Werner K.,Buss P.,Baertsch A.,Caviezel M.

Publisher

Springer US

Reference20 articles.

1. Beland, F.A., N.F. Fullerton, T. Kinouchi, and M.C. Poirier, (1988) DNA adduct formation during continuous feeding of 2-acetyl-aminofluorene at multiple concentrations. IARC Sci. Publ. 89:175–180.

2. Belinsky, S.A., CM. White, T.R. Devereux, J.A. Swenberg, and M.W. Anderson (1987) Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N -nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res. 47:1143–1148.

3. Berger, M.R., D. Schmaehl, and H. Zerban (1987) Combination experiments with very low doses of three genotoxic N-nitrosamines with similar organotropic carcinogenicity in rats. Carcinogenesis 8:1635–1643.

4. Boucheron, J. A., F.C. Richardson, P.H. Morgan, and J. A. Swenberg (1987) Molecular dosimetry of 04-ethyldeoxythymidine in rats continuously exposed to diethylnitrosamine. Cancer Res. 47:1577–1581.

5. Cairns, T. (1979) The ED01 study: Introduction, objectives, and experimental design. In Innovations in Cancer Risk Assessment (ED01 Study). Pathotox Publishers, Park Forest South, IL 60466 USA, pp. 1–8.

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