Functional and Structural Evaluation after AAV.RPE65 Gene Transfer in the Canine Model of Leber’s Congenital Amaurosis

Author:

Narfström Kristina,Bragadóttir Ragnheidur,Redmond T. Michael,Rakoczy P. Elizabeth,van Veen Theo,Bruun Anitha

Publisher

Springer US

Reference16 articles.

1. Acland, G.M., Aguirre, G.D., Ray, J. et al., 2001, Gene therapy restores vision in a canine model of childhood blindness, Nat Genet. 28:92–95.

2. Aguirre,G., Baldwin,V., Pearce-Kelling, S.et al.,1994, Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect, Mol Vis. 4:23.

3. Gery, I., Mochizuki, M., and Nussenblatt, R.B., 1986, Retinal specific antigens and immunopathogenic processes they provoke. In:Progress in Retinal Research, Osborne N, Chader,G, eds. Pergamon Press, Oxford. 75–109.

4. Gu,. S.-G., Thompson, D.A., Srikumari, C.R.S., et al., 1997, Mutations in the RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy. Nat Genet. 17:194–197.

5. Ham, D.I., Gentleman, S., Chan, C., et al., 2002, RPE65 is highly uveitogenic in rats. Invest Ophthalmol. Vis Sci. 43:2258–2263.

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