Inhibition by 3′-Azido-3′-Deoxythymidine (AZT) of trypanosoma Cruzi Growth in Mammalian Cells and a Possible Mechanism of Action

Author:

Nakajima-Shimada Junko,Aoki Takashi

Publisher

Springer US

Reference7 articles.

1. Aoki, T., Nakajima-Shimada, J., and Hirota, Y. (1995): Quantitative determination of Trypanosoma cruzi growth inside host cells in vitro and effect of allopurinol. Adv. Exp. Med. Biol., 370, 499–502.

2. Marr, J.J., and Berens, R.L. (1983): Pyrazolopyrimidine metabolism in the pathogenic Trypanosomatidae. Mol. Biochem. Parasitol., 7, 339–356.

3. Nakajima-Shimada, J., Hirota, Y., Kaneda, Y., and Aoki, T. (1994): Quantitative determination of growth of amas-tigotes and trypomastigotes in an in vitro cultivation system of HeLa cells infected with Trypanosoma cruzi. J. Protozool. Res., 4, 10–17.

4. Nakajima-Shimada, J., Hirota, Y, and Aoki, T. (1996): Inhibition of Trypanosoma cruzi growth in mammalian cells by purine and pyrimidine analogs. Antimicrob. Agents Chemother., 40, 2455–2458.

5. Solari, A., Tharaud, D., Repetto, Y., Aldunate, J., Moewllo, A., and Litvak, S. (1983): In vitro and in vivo studies of Trypanosoma cruzi DNA polymerase. Biochem. Int., 7, 147–157.

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