Fibroblast Growth Factors (FGFS) Increase Breast Tumor Growth Rate, Metastases, Blood Flow, and Oxygenation Without Significant Change in Vascular Density

Author:

Okunieff Paul,Fenton Bruce M.,Zhang Lurong,Kern Francis G.,Wu Timothy,Greg J. Robert,Ding Ivan

Publisher

Springer US

Reference11 articles.

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2. Folkman J. A new family of mediators of tumor angiogenesis, Cancer Invest 2001;19:754–755.

3. Kurebayashi J, McLeskey SW, Johnson MD, Lippman ME, Dickson RB, Kern FG. Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ, Cancer Res 1993;53:2178–2187.

4. McLeskey S W, Kurebayashi J, Honig SF, Zwiebel J, Lippman ME, Dickson RB, Kern FG Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice, Cancer Res 1993;53:2168–2177.

5. Zhang L, Kharbanda S, Chen D, Bullocks J, Miller DL, Ding IY, Hanfelt J, McLeskey S W, Kern FG. MCF-7 breast carcinoma cells overexpressing FGF-1 form vascularized, metastatic tumors in ovariectomized or tamoxifen-treated nude mice, Oncogene 1997;15:2093–108..

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