Regulation of Polyamine Biosynthetic Activity and Homeostasis as a Novel Antiproliferative Strategy

Author:

Porter Carl W.,Kramer Debora L.,Bernacki Ralph J.,Bergeron Raymond J.

Publisher

Springer US

Reference43 articles.

1. Janne J, Poso H, Raina, A: Polyamines in rapid growth and cancer. Biochim. Biophys. Acta 473:241–293, 1978.

2. Porter CW, Sufrin JR: Interference with polyamine biosynthesis and/or function by analogs of polyamines or methionine as a potential anticancer chemotherapeutic strategy: A review. Anticancer Res. 6:525–542, 1986.

3. Pegg AE: Perspectives in Cancer Research. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res. 48:759–774, 1988.

4. Porter CW, Bergeron RJ: Enzyme regulation as an approach to interference with polyamine biosynthesis — an alternative to enzyme inhibition. In: Advances in Enzyme Regulation. G Weber (ed), Pergamon Press, New York and Oxford, Vol. 27, pp. 57–79, 1988.

5. Kingsnorth AN, King WWK, Diekema KA et al: Inhibition of ornithine decarboxylase with 2-difluoromethylornithine: Reduced incidence of dimethylhydrazine-induced colon tumors in mice. Cancer Res. 43:2545–2549, 1983.

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