An asymptotic model for the primary drying stage of vial lyophilization-Reference-Cited by-同舟云学术

An asymptotic model for the primary drying stage of vial lyophilization

Published:2015-05-20 Issue:1 Volume:96 Page:175-200
ISSN:0022-0833
Container-title:Journal of Engineering Mathematics
language:en
Short-container-title:J Eng Math

Author:

Vynnycky M.

Publisher

Springer Science and Business Media LLC

Subject

General Engineering,General Mathematics

Link

http://link.springer.com/content/pdf/10.1007/s10665-015-9789-7.pdf

Reference30 articles.

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2. Sheehan P, Liapis AI (1998) Modelling of the primary and secondary drying stages of the freeze-drying of pharmaceutical product in vials: numerical results obtained from the solution of a dynamic and spatially multidimensional lyophilisation model for different operational policies. Biotechnol Bioeng 60:712–728

3. Pikal MJ, Cardon S, Bhugra C, Jameel F, Rambhatla S, Mascarenhas WJ, Akay HU (2005) The nonsteady state modeling of freeze drying: in-process product temperature and moisture content mapping and pharmaceutical product quality applications. Pharm Dev Tech 1:17–32

4. Pikal MJ (1985) Use of laboratory data in freeze-drying process design: heat and mass transfer coefficients and the computer simulation of freeze-drying. J Parenter Sci Tech 39:115–139

5. Millman MJ, Liapis AI, Marchello JM (1985) An analysis of the lyophilisation process using a sorption sublimation model and various operational policies. AIChE J 31:1594–1604

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