Performance of a membrane-dialysis bioreactor with a radial-flow fixed bed for the cultivation of a hybridoma cell line
Author:
Publisher
Springer Science and Business Media LLC
Subject
Applied Microbiology and Biotechnology,General Medicine,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/BF02431907.pdf
Reference28 articles.
1. Adamson SR, Fitzpatrick SL, Gaucher GM, Lesser BH (1983) In vitro production of high titer monoclonal antibody by hybridoma cells in dialysis cultures. Biotechnol Lett 5: 573–578
2. Altshuler GL, Dziewulski DM, Sowek JA, Belfort G (1986) Continuous hybridoma growth and monoclonal antibody production in hollow fiber reactors-separators. Biotechnol Bioeng 28: 646–658
3. Belfort G (1989) Membranes and bioreactors:a technical challenge in biotechnology. Biotechnol Bioeng 33: 1047–1066
4. Bohmann A, Pörtner R, Schmieding J, Kasche V, Märkl H (1992) The membrane dialysis bioreactor with integrated radial-flow fixed bed — a new approach for continuous cultivation of animal cells. Cytotechnology 9: 51–57
5. Büntemeyer H, Lütkemeyer D, Lehmann J (1991) Optimization of serum-free fermentation processes for antibody production; Cytotechnology 5: 57–67
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