Inhibition of phospholipase A2 (PLA2) activity by nifedipine and nisoldipine is independent of their calcium-channel-blocking activity

Author:

Chang Joseph,Blazek Eileen,Carlson Richard P.

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference22 articles.

1. Janis, R. A., andA. Scriabine. 1985. Sites of action of Ca2 channel inhibitors.Biochem. Pharmacol. 33:3499?3506.

2. Elferink, J. G. R. 1982. Interference of the calcium antagonists verapamil and nifedipine with lysosomal enzyme release from rabbit polymorphonuclear leukocytes.Arzneim.-Forsch/ Drug Res. 32:1417?1420.

3. Simchowitz, L., andI. Spilberg. 1979. Generation of superoxide radicals by human peripheral neutrophils activated by chemotatic factor. Evidence for the role of calcium.J. Lab. Clin. Med. 93:583?593.

4. Stocker, R., andC. Richter. 1982. Involvement of calcium, calmodulin and phospholipase A in the alteration of membrane dynamics and superoxide production of human neutrophils stimulated by phorbol myristate acetate.FEBS Lett. 147:243?246.

5. Ikeda, Y., M. Kikuchi, K. Toyama, K. Watanabe, andY. Ando. 1981. Effects by nifedipine on platelet function in vivo and in vitro.Thromb. Haemostas. 45:158?164.

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