Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis
Author:
Funder
American Heart Association
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Pediatrics, Perinatology, and Child Health
Link
https://link.springer.com/content/pdf/10.1007/s00246-020-02427-7.pdf
Reference44 articles.
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2. Sowunmi A, Fehintola FA, Adedeji AA et al (2004) Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children. Trop Med Int Health 9:606–614. https://doi.org/10.1111/j.1365-3156.2004.01233.x
3. Koch SE, Tranter M, Robbins N et al (2013) Probenecid as a noninjurious positive inotrope in an ischemic heart disease murine model. J Cardiovasc Pharmacol Ther 18:280–289. https://doi.org/10.1177/1074248412469299
4. Koch SE, Gao X, Haar L et al (2012) Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation. J Mol Cell Cardiol 53:134–144. https://doi.org/10.1016/j.yjmcc.2012.04.011
5. Robbins N, Gilbert M, Kumar M et al (2018) Probenecid improves cardiac function in patients with heart failure with reduced ejection fraction in vivo and cardiomyocyte calcium sensitivity in vitro. J Am Heart Assoc. https://doi.org/10.1161/JAHA.117.007148
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