In Mixed Lymphocyte Reaction, the Hypoxia-Inducible Factor Prolyl-Hydroxylase Inhibitor Roxadustat Suppresses Cellular and Humoral Alloimmunity
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Immunology,Immunology and Allergy
Link
https://link.springer.com/content/pdf/10.1007/s00005-020-00596-0.pdf
Reference59 articles.
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3. Akizawa T, Iwasaki M, Yamaguchi Y et al (2020) Phase 3, randomized, double-blind, active-comparator (darbepoetin alfa) study of oral roxadustat in CKD patients with anemia on hemodialysis in Japan. J Am Soc Nephrol 31:1628–1639. https://doi.org/10.1681/asn.2019060623
4. Beck J, Henschel C, Chou J et al (2017) Evaluation of the carcinogenic potential of roxadustat (FG-4592), a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase in CD-1 mice and sprague dawley rats. Int J Toxicol 36:427–439. https://doi.org/10.1177/1091581817737232
5. Ben-Shoshan J, Maysel-Auslender S, Mor A et al (2008) Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α. Eur J Immunol 38:2412–2418. https://doi.org/10.1002/eji.200838318
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1. Hypoxia-inducible factors: details create a picture. Part II. HIF-2;Fundamental and Clinical Medicine;2024-01-02
2. Roxadustat: do we know all the answers?;Biomolecules and Biomedicine;2023-01-03
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4. Authors’ Reply;Journal of the American Society of Nephrology;2021-04-13
5. On the Increased Event Rate of Urinary Tract Infection and Pneumonia in CKD Patients Treated with Roxadustat for Anemia;Journal of the American Society of Nephrology;2021-04-13
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