Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Physiology
Link
http://link.springer.com/content/pdf/10.1007/s10863-012-9413-8.pdf
Reference40 articles.
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4. Chang GG, Hsu RY (1977) Mechanism of pigeon liver malic enzyme: kinetics, specificity, and half-site stoichiometry of the alkylation of a cysteinyl residue by the substrate-inhibitor bromopyruvate. Biochemistry 16:311–320
5. da-Silva WS, Gómez-Puyou AP, Gómez-Puyou MT, Moreno-Sanchez R et al (2004) Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense: steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria. J Biol Chem 279:39846–39855
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