Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine, prodrugs of 3-methyl-(triazen-1-yl)imidazole-4-carboxamide

Author:

Tsang Lincoln L. H.,Quarterman Charmaine P.,Gescher Andreas,Slack John A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference16 articles.

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2. Bill CA, Gescher A, Hickman JA (1988) Effects ofN-methylformamide on the growth, cell cycle, and glutathione status of murine TLX5 lymphoma cells. Cancer Res 48: 3389

3. Boyle W (1968) An extension of the51Cr release assay for the estimation of mouse cytotoxins. Transplantation 6: 761

4. Connors TA, Goddard PM, Merai K, Ross WCJ, Wilman DEV (1976) Tumour inhibitory triazenes. Structural requrements for an active metabolite. Biochem Pharmacol 25: 241

5. Gescher A, Thradgill MD (1987) The metabolism of triazene antitumor drugs. Pharmacol Ther 32:191

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