Pharmacokinetics of irinotecan and its metabolites in human blood, bile, and urine

Author:

Lokiec Fran�ois,Canal Pierre,Gay Croisine,Chatelut Etinne,Armand Jean-Pierre,Roch� Henri,Bugat Roland,Gon�alv�s Emanuel,Mathieu-Bou� Anne

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference10 articles.

1. Barilero I, Gandia D, Armand JP, Mathieu-Boué A, Ré M, Gouyette A, Chabot GG (1992) Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high performance liquid chromatography: application to plasma pharmacokinetic studies in cancer patients. J Chromatogr 75: 275

2. Gay C, Lokiec F, Canal P, Bonneterre J, Bugat R, Tubiana-Hulin M, Mathieu-Boué A (1994) Pharmacolinetics and pharmacodynamics of the camptothecin analogue CPT-11 during phase II studies. Proc Am Assoc Cancer Res 35: 243

3. Kaneda N, Yokokura T (1990) Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res 50: 1721

4. Kaneda N, Nagata H, Furuta T, Yokokura T (1990) Metabolism and pharmacokinetics of the campothecin analogue CPT-11 in the mouse. Cancer Res 50: 1715

5. Kawato Y, Aonuma M, Hirota Y, Kuga H, Sato K (1991) Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51: 4187

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